Title: Plasma citrulline concentration: A surrogate end point for radiation-induced mucosal atrophy of the small bowel. A feasibility study in 23 patients
Authors: Lutgens, LCHW ×
Deutz, N
Granzier-Peeters, M
Beets-Tan, R
De Ruysscher, Dirk
Gueulette, J
Cleutjens, J
Berger, M
Wouters, B
von Meyenfeldt, M
Lambin, Philippe #
Issue Date: Sep-2004
Publisher: Pergamon Press
Series Title: International Journal of Radiation Oncology, Biology, Physics vol:60 issue:1 pages:275-285
Abstract: Purpose: Plasma citrulline, a nitrogen end product of glutamine metabolism in small-bowel enterocytes, was suggested as a marker of radiation-induced small-bowel epithelial cell loss in mice after single-dose whole-body irradiation. Our objective was to evaluate the feasibility of citrulline as a marker for radiation-induced small-intestinal mucosal atrophy in patients during and after abdominal fractionated radiotherapy.
ISSN: 0360-3016
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Oncology - miscellaneous
Laboratory of Experimental Radiotherapy
× corresponding author
# (joint) last author

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