Title: [Prevention using pefloxacin of infections in cancer patients with granulocytopenia]
Authors: Leleux, A ×
Snoeck, Robert
Gerain, J
Van der Auwera, P
Daneau, D
Meunier, F #
Issue Date: 1989
Series Title: Presse médicale (Paris, France vol:18 issue:1 pages:21-4
Abstract: The practical procedures of digestive tract decontamination and prophylaxis of bacterial infection in granulocytopenic patients are debated. Fluoroquinolones are active against Gram-negative bacilli and have few side-effects. Pefloxacin was administered prophylactically to patients with cancer and granulocytopenia. None of them developed Gram-negative septicaemia, but 2 cases of streptococcal septicaemia were observed. The drug was well tolerated by all patients except one. Studies are currently in progress to try to reduce the incidence of septicaemia caused by Gram-positive cocci, using pefloxacin combined with penicillin.
ISSN: 0755-4982
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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