To investigate the effects of muscle fatigue on force sense at the ankle joint, 10 young healthy adults were asked to perform an isometric contra-lateral force ankle-matching task in two experimental conditions of: (1) no-fatigue and (2) fatigue of the plantar-flexor muscles. Measures of the overall accuracy and the variability of the force matching performances were determined using the absolute error and the variable error, respectively. Results showed less accurate and less consistent force matching performances in the fatigue than 110 fatigue condition, as indicated by decreased absolute and variable errors, respectively. The present findings evidence that muscle fatigue degrades force sense at the ankle joint. (c) 2008 Elsevier B.V. All rights reserved.