Title: Biomechanical effects of polyglecaprone fibers in a polypropylene mesh after abdominal and rectovaginal implantation in a rabbit
Authors: Ozog, Yves ×
Mazza, Edoardo
De Ridder, Dirk
Deprest, Jan #
Issue Date: Oct-2012
Publisher: Springer International
Series Title: International urogynecology journal vol:23 issue:10 pages:1397-402
Abstract: INTRODUCTION AND HYPOTHESIS: To investigate the biomechanical effects of polyglecaprone fibers in lightweight meshes implanted into the vaginal and abdominal wall of parous rabbits. METHODS: New Zealand White rabbits (n = 24) were implanted with polypropylene meshes (32 g/m(2)), with (Prolift plus M, n = 12) or without (Prolift minus M, n = 12) polyglecaprone fibers. Following implantation in the posterior vaginal and abdominal wall, local side effects were evaluated and explants underwent uniaxial tensiometry after 120 and 180 days. RESULTS: The vaginal extrusion rate was at least 50 %, coinciding with a minimum of 20 % of contraction. There were no measurable effects of the addition of polyglecaprone on tensiometric strength and compliance in abdominal explants. CONCLUSIONS: The addition of polyglecaprone fibers did not compromise the biomechanical properties nor did it prevent vaginal extrusion and contraction. The latter as well as some other limitations preclude the rabbit vagina to be a suitable model for biomechanical testing.
ISSN: 0937-3462
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pregnancy, Foetus and Newborn (-)
× corresponding author
# (joint) last author

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