Title: Bicyclic nucleoside inhibitors of varicella-zoster virus (VZV): the effect of terminal unsaturation in the side chain
Authors: Srinivasan, S ×
McGuigan, C
Andrei, Graciela
Snoeck, Robert
De Clercq, Erik
Balzarini, Jan #
Issue Date: Feb-2001
Series Title: Bioorganic & medicinal chemistry letters vol:11 issue:3 pages:391-3
Abstract: Novel bicyclic nucleoside analogues bearing long alkyl side chains are prepared and tested as inhibitors of VZV. In particular, analogues with terminal unsaturation in the side chain are reported. Whilst terminal alkenyl derivatives are potent antivirals, the corresponding terminal alkynyls are poorly active.
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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