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Title: Isolation and characterization of Locusta migratoria accessory gland myotropin I (Lom-AG-MT-I) from the brain of the Colorado potato beetle, Leptinotarsa decemlineata
Authors: Spittaels, Kurt ×
Vankeerberghen, Anne
Schoofs, Liliane
Proost, Paul
Van Damme, Jozef
De Loof, Arnold #
Issue Date: Jan-1996
Publisher: John Wiley & Sons
Series Title: Archives of Insect Biochemistry and Physiology vol:31 issue:2 pages:149-155
Abstract: A novel myotropic Colorado potato beetle peptide, active in the Locusta oviduct motility assay, was isolated from a methanolic extract of 9,000 brain complexes of adult Leptinotarsa decemlineata by means of HPLC. Its sequence is Gly-Phe-Lys-Asn-Val-Ala-Leu-Ser-Thr-Ala-Arg-Gly-Phe-NH2. This peptide is identical to Lom-AG-MT-I, a myotropin previously isolated from the male accessory glands of Locusta migratoria, using the L. migratoria oviduct motility bioassay as a monitoring system. It strongly stimulated the frequency, amplitude, and tonus of the myogenic oviduct contractions, even at low concentrations.
ISSN: 0739-4462
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Animal Physiology and Neurobiology Section - miscellaneous
Academic Center for General Practice
Laboratory of Molecular Immunology (Rega Institute)
Department of Biology - miscellaneous
× corresponding author
# (joint) last author

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