Title: Aneuploidy and Copy Number Variation in Early Human Development
Authors: Vanneste, Evelyne
Van der Aa, Niels
Voet, Thierry
Vermeesch, Joris # ×
Issue Date: Aug-2012
Publisher: Thieme Medical Publishers
Series Title: Seminars in Reproductive Medicine vol:30 issue:4 pages:302-308
Abstract: Early human in vitro fertilized embryos frequently accumulate whole chromosome aneuploidies and segmental imbalances. This embryonic chromosomal instability does not necessarily undermine normal human development, but it may lead to loss of conception, genetic disease, and genetic variation development. In this review we provide an overview of how this instability of chromosomes arises and evolves during early human embryogenesis.
ISSN: 1526-8004
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Human Genetics - miscellaneous
Laboratory for Cytogenetics and Genome Research
Laboratory of Reproductive Genomics
× corresponding author
# (joint) last author

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