Title: Morphology and function of Bast's valve: additional insight in its functioning using 3D-reconstruction
Authors: Hofman, R ×
Segenhout, J. M
Buytaert, Jan
Dirckx, J. J. J
Wit, H. P #
Issue Date: Feb-2008
Publisher: Springer International
Series Title: European Archives of Oto-Rhino-Laryngology vol:265 issue:2 pages:153-157
Abstract: The utriculo-endolymphatic valve was discovered by Bast in 1928. The function of Bast's valve is still unclear. By means of orthogonal-plane fluorescence optical sectioning (OPFOS) microscopy 3D-reconstructions of the valve and its surrounding region are depicted. The shape of the duct at the utricular side is that of a flattened funnel. In the direction of the endolymphatic duct and sac this funnel runs into a very narrow duct. The valve itself has a rigid 'arch-like' configuration. The opposing thin, one cell-layer thick, utricular membrane is highly compliant. We propose that opening and closure of the valve occurs through movement of the flexible base/utricular membrane away from and toward the relatively rigid valve lip.
ISSN: 0937-4477
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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