No mucosal atrophy and reduced inflammatory cells: active-controlled trial with yearlong fluticasone furoate nasal spray
Fokkens, Wytske J × Rinia, Bas van Drunen, Cornelis M Hellings, Peter Hens, Greet Jansen, Ad Blom, Henk Wu, Wei Clements, Diane S Lee, Laurie A Philpot, Edward E #
OceanSide Publications, Inc.
American Journal of Rhinology & Allergy vol:26 issue:1 pages:36-44
Fluticasone furoate nasal spray (FFNS) and mometasone furoate nasal spray (MFNS) are well tolerated and more effective than placebo at relieving the symptoms of seasonal and perennial allergic rhinitis. Effects of FFNS on the nasal histology have not been previously reported. This study examines the effects of FFNS and MFNS, administered daily for 1 year, on the nasal mucosa in subjects with perennial allergic rhinitis.