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Title: Sequence analysis and evolution of group B rotaviruses
Authors: Rahman, Mustafizur ×
Hassan, Zahid M
Zafrul, Hasan
Saiada, Farjana
Banik, Sukalyani
Faruque, Abu S G
Delbeke, Thomas
Matthijnssens, Jelle
Van Ranst, Marc
Azim, Tasnim #
Issue Date: Feb-2007
Publisher: Elsevier
Series Title: Virus research vol:125 issue:2 pages:219-225
Abstract: Human group B rotaviruses were isolated from hospitalized patients in Bangladesh between July 2003 and December 2004. Phylogenetic analyses of the gene segments encoding the hemagglutinin (VP4), glycoprotein (VP7) and RNA-binding protein (NSP2) of group B rotaviruses showed that Bangladeshi strains were more similar to the Indian strains than to the prototype Chinese strains. Moreover, all human strains were clustered together and were distantly related to the animal strains. With limited sequence data, the evolutionary rate of the glycoproteins (VP7) of human group B rotaviruses was estimated to be 1.57x10(-3)nucleotide substitutions/(siteyear), which was comparable to other rapidly evolving RNA viruses. The most recent common ancestor (MRCA) of the extant human group B rotaviruses was calculated to date to around 1976.
URI: 
ISSN: 0168-1702
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
Laboratory of Clinical Bacteriology and Mycology
× corresponding author
# (joint) last author

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