Title: Synthesis and antiviral evaluation of benzimidazoles, quinoxalines and indoles from dehydroabietic acid
Authors: Fonseca, Tatiana ×
Gigante, Bárbara
Marques, M Matilde
Gilchrist, Thomas L
De Clercq, Erik #
Issue Date: Jan-2004
Series Title: Bioorganic & medicinal chemistry vol:12 issue:1 pages:103-12
Abstract: Several heterocycles, such as benzimidazoles, quinoxalines and indoles incorporated into a hydrophenanthrene and naphthalene skeleton, were synthesised from two useful ortho-bromonitro precursors derived from dehydroabietic acid: methyl 12-bromo-13-nitro-deisopropyldehydroabietate and methyl 12-bromo-13,14-dinitro-deisopropyldehydroabietate. The new heterocycles were evaluated for their activity in vitro against several RNA and DNA viruses.
ISSN: 0968-0896
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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