Title: Upregulation of transient receptor potential vanilloid type-1 receptor expression in oral lichen planus
Authors: Bán, Agnes ×
Marincsák, Rita
Bíró, Tamás
Perkecz, Anikó
Gömöri, Eva
Sándor, Katalin
Tóth, Balázs István
Bánvölgyi, Agnes
Szolcsányi, János
Pintér, Erika #
Issue Date: 2010
Publisher: S. Karger Medical and Scientific Publishers
Series Title: Neuroimmunomodulation vol:17 issue:2 pages:103-8
Abstract: Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa. Its etiology is still unclear. Neurogenic components might contribute to the inflammatory process. The oral mucosa is richly innervated by sensory fibers. Mediators secreted by inflammatory cells activate sensory nerves via transient receptor potential vanilloid receptor 1 (TRPV1) and lead to the release of neuropeptides. So far, TRPV1 receptor expression was detected on neurons. Only recently, TRPV1 receptors were identified in nonneuronal tissues. The aim of the present study was to detect the presence of TRPV1 receptors and peripheral expression of receptor mRNA in normal oral mucosa and mucous membranes from OLP patients.
ISSN: 1021-7401
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Ion Channel Research
× corresponding author
# (joint) last author

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