Increased expression of TRPV1 in squamous cell carcinoma of the human tongue
Marincsák, R × Tóth, Balázs István Czifra, G Márton, I Rédl, P Tar, I Tóth, L Kovács, L Bíró, T #
Oral Diseases vol:15 issue:5 pages:328-35
Recent reports have unambiguously identified the presence and the growth-modulatory role of transient receptor potential vanilloid-1 (TRPV1), a central integrator of pain sensation, on numerous non-neuronal cell types and, of great importance, in certain malignancies. In this study, we have investigated the molecular expression of TRPV1 in the human tongue and its high-incidence malignant (squamous cell carcinoma, SCC) and premalignant (leukoplakia) conditions.