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Title: The biological basis of fractionation
Authors: Haustermans, Karin ×
Withers, H Rodney #
Issue Date: 2004
Series Title: Rays vol:29 issue:3 pages:231-236
Abstract: A few important concepts in radiobiology are illustred. The cell survival, the concept of the biologically effective dose, the basis of fractionation in radiotherapy are considered. Slow tumor regression after irradiation is not an indication of treatment failure, and the rate of regression is not , in general, prognostic. Dose volume histograms provide many data for predicting tumor control and side effects. The magnitude of a dose reduction in the tumor is the major determinant of decline in tumor control probability. Escalation of dose to hypoxic foci may be beneficial. Basic knowledge of these concepts is essential for daily radiotherapy practice and for all radiation oncologists.
ISSN: 0390-7740
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Experimental Radiotherapy
× corresponding author
# (joint) last author

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