Title: Age-related impairment of ultrasonic vocalization in Tau.P301L mice: possible implication for progressive language disorders
Authors: Menuet, Clément ×
Cazals, Yves
Gestreau, Christian
Borghgraef, Peter
Gielis, Lies
Dutschmann, Mathias
Van Leuven, Fred
Hilaire, Gérard #
Issue Date: 2011
Publisher: Public Library of Sciene
Series Title: PLoS One vol:6 issue:10 pages:e25770
Abstract: Tauopathies, including Alzheimer's Disease, are the most frequent neurodegenerative diseases in elderly people and cause various cognitive, behavioural and motor defects, but also progressive language disorders. For communication and social interactions, mice produce ultrasonic vocalization (USV) via expiratory airflow through the larynx. We examined USV of Tau.P301L mice, a mouse model for tauopathy expressing human mutant tau protein and developing cognitive, motor and upper airway defects.
ISSN: 1932-6203
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Experimental Genetics and Transgenesis (-)
Department of Human Genetics - miscellaneous
× corresponding author
# (joint) last author

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