Title: Resiniferatoxin mediated ablation of TRPV1+ neurons removes TRPA1 as well
Authors: Pecze, László ×
Pelsoczi, Péter
Kecskes, Miklos
Winter, Zoltán
Papp, András
Kaszás, Krisztián
Letoha, Tamás
Vizler, Csaba
Oláh, Zoltán #
Issue Date: Mar-2009
Publisher: Canadian Journal of Neurological Sciences
Series Title: Canadian Journal of Neurological Sciences vol:36 issue:2 pages:234-41
Abstract: Resiniferatoxin, the most potent agonist of inflammatory pain/vanilloid receptor/cation channel (TRPV1) can be used for neuron subtype specific ablation of pain generating cells at the level of the peripheral nervous system by Ca(2+)-excytotoxicity. Molecular neurosurgery is an emerging technology either to alleviate severe pain in cancer or treat/prevent different local neuropathies. Our aim was determining sensory modalities that may be lost after resiniferatoxin treatment.
ISSN: 0317-1671
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Ion Channel Research
× corresponding author
# (joint) last author

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