Title: Does sucralfate reduce early side effects of pelvic radiation? A double-blind randomized trial
Authors: Stellamans, Karin ×
Lievens, Yolande
Lambin, Philippe
Van den Weyngaert, Danielle
Van den Bogaert, Walter
Scalliet, Pierre
Hutsebaut, Liesbeth
Haustermans, Karin #
Issue Date: Nov-2002
Publisher: Elsevier Science Publishers
Series Title: Radiotherapy and Oncology vol:65 issue:2 pages:105-108
Abstract: STUDY AND METHODS: A double-blind placebo-controlled study randomized 108 patients to investigate the effect of sucralfate on gastrointestinal side effects of pelvic radiation. RESULTS: Overall, pelvic radiation with the administered doses and fields and performed according to nowadays technical standards, was well tolerated. Comparison of the mean scores and the peak reactions for radiotherapy discomfort, diarrhoea and number of stools per day in the 80 evaluable patients showed no statistically significant difference between sucralfate and placebo. CONCLUSION: Based on these results, the use of sucralfate can not be recommended as standard practice.
ISSN: 0167-8140
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Experimental Radiotherapy
× corresponding author
# (joint) last author

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