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Abstract:

Objectives: To determine the effect of chlorhexidine-digluconate (CHX) and galardine (G) – common MMP-Inhibitors – on microtensile bond strength (ìTBS). Methods: Ceramic specimens were cemented to bur –cut dentin surfaces with the self-adhesive (SA) materials RelyX Unicem 2 (RLX, 3M Espe) and Clearfil SA (CSA, Kuraray) or the etch & rinse based Nexus 3 (NX, Kerr). The surfaces were pretreated with either 2% CHX or 0.2 mM G, and one-week- ìTBS was determined. Results: 2 way-ANOVA revealed a significant difference between the resin cements (p<0.001), but no effect of pre-treatment (p=0.1688). However, the ìTBS of NX was significantly lower compared to NX/CHX (p=0.0022), for RLX and RLX/CHX it was contrary (p=0.0010, Tukey multiple comparisons). G had no effect on ìTBS. Conclusion: The effect of CHX on MTBS to dentin is dependent on the type of resin cement, but G had no effect on immediate ìTBS.