Title: Modeling the effect of repositioning on the evolution of skeletal muscle damage in deep tissue injury
Authors: Demol, Jan
Van Deun, Dorien
Haex, Bart
Van Oosterwyck, Hans
Vander Sloten, Jos # ×
Issue Date: 2013
Publisher: Springer
Series Title: Biomechanics and Modeling in Mechanobiology vol:12 issue:2 pages:267-279
Abstract: Deep tissue injury (DTI) is a localized area of tissue necrosis that originates in the subcutaneous layers under an intact skin and tends to develop when soft tissue is compressed for a prolonged period of time. In clinical practice, DTI is particularly common in bedridden patients and remains a serious issue in today’s healthcare. Repositioning is generally considered to be an effective preventive measure of pressure ulcers. However limited experimental research and no computational studies have been undertaken on this method. In this study, a methodology was developed to evaluate the influence of different repositioning intervals on the location, size and severity of DTI in bedridden patients. The spatiotemporal evolution of compressive stresses and skeletal muscle viability during the first 48 hours of DTI onset were simulated for repositioning schemes in which a patient is turned every 2, 3, 4 or 6 hours. The model was able to reproduce important experimental findings, including the morphology and location of DTI in human patients as well as the discrepancy between the internal tissue loads and the contact pressure at the interface with the environment. In addition, the model indicated that the severity and size of DTI were reduced by shortening the repositioning intervals. In conclusion, the computational framework presented in this study provides a promising modeling approach that can help to objectively select the appropriate repositioning scheme that is effective and efficient in the prevention of DTI.
ISSN: 1617-7959
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Biomechanics Section
Technology Transfer - miscellaneous
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science