Title: Palladium catalyzed synthesis of Ca2+ indicators with aryl bithiophene and terthiophene fluorophores
Authors: Boens, Noël ×
Avcibasi, N
Samanta, SS
Kilonda, Amuri
Hoornaert, GJ
Van der Eycken, Erik #
Issue Date: Jan-2006
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:62 issue:4 pages:684-690
Abstract: Five new fluorescent indicators for Ca2+ were synthesized using the Stille reaction. They all consist of the tricarboxylate chelator APTRA (o-aminophenol-N,N,O-triacetic acid) linked to a (substituted) bithiophene or terthiophene fluorophore. The dissociation constants K-d measured via fluorimetric titrations at 21 degrees C in 100 mM KCl buffered solution, pH 7.05, for the Ca2+ complexes with the new probes are in the range between 10 and 40 mu M. (c) 2005 Elsevier Ltd. All rights reserved.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
Molecular Imaging and Photonics
× corresponding author
# (joint) last author

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