Title: Does the presence of a Caesarean section scar influence the site of placental implantation and subsequent migration in future pregnancies: A prospective case-control study
Authors: Naji, O ×
Daemen, Anneleen
Smith, A
Abdallah, Y
Bradburn, E
Giggens, R
Chan, Dcy
Stalder, C
Ghaem-Maghami, S
Timmerman, Dirk
Bourne, Tom #
Issue Date: Nov-2012
Publisher: Blackwell Science
Series Title: Ultrasound in Obstetrics & Gynecology vol:40 issue:5 pages:557-561
Article number: 10.1002/uog.11133
Abstract: OBJECTIVES: To describe placental location in the first trimester and subsequent placental migration in women with and without a history of previous Caesarean delivery. METHODS: In this prospective case-control study, placental location was defined according to 5 anatomical sites in relation to the endometrial cavity. Placental localisation was carried out by transabdominal ultrasound between 11 and 14 weeks gestation. We recruited 738 women who had undergone one or more previous Caesarean sections (CS) and 1856 patients without previous Caesarean delivery. Chi-square test was used to perform comparative analysis of placental location between the two groups, and to assess placental migration of those classified as being low-lying at 20 and 32 weeks gestation. RESULTS: There were significant differences in placental location between the two groups. In the Caesarean group there were significantly more posterior and fewer fundal placentas than in the control group, (47.2 vs. 31.5% and 4.7 vs. 15.5%, respectively). The number of previous Caesarean deliveries did not have a significant effect on placental location. The incidence of anterior low-lying placenta was greater in the Caesarean group than the control group (1.5% vs. 0.9%). Placental migration of the low-lying subtypes was similar in both groups (61% vs. 64%). CONCLUSION: The presence of a CS scar in the uterus is associated with an increase in the number of posterior placentas and a reduced number that implant in the fundus of the cavity. There is also an increase in the number of low-lying anterior placentas in the CS group. Migration of a low-lying placenta is independent of the presence of a Caesarean scar in the uterus. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd.
ISSN: 0960-7692
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Development and Regeneration - miscellaneous (+)
× corresponding author
# (joint) last author

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