Block, S × Baccelli, C Tinant, B Van Meervelt, Luc Rozenberg, R Jiwan, JLH Llabres, G De Pauw-Gillet, MC Quetin-Leclercq, J #
Pergamon-elsevier science ltd
Phytochemistry vol:65 issue:8 pages:1165-1171
Two new trachylobane- and one isopimarane-type diterpenoids: ent-18-hydroxy-trachyloban-3-one; ent-trachyloban-3-one-, isopimara-7,15-dien-3beta-ol, were isolated from the leaves of Croton zambesicus, together with trans-phytol, beta-sitosterol, alpha-amyrin and stigmasterol. The structures were determined by extensive NMR techniques and X-ray analysis. The cytotoxicity of these compounds has been evaluated on cancer and non-cancer cell-lines. (C) 2004 Elsevier Ltd. All rights reserved.