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Title: Fetoscopic Laser Surgery for Twin-to-Twin Transfusion Syndrome after 26 Weeks of Gestation
Authors: Valsky, Dan V ×
Eixarch, Elisenda
Martinez-Crespo, Josep M
Acosta, Emilia-Ruthy
Lewi, Liesbeth
Deprest, Jan
Gratacós, Eduard #
Issue Date: 9-Dec-2012
Publisher: S. Karger
Series Title: Fetal Diagnosis and Therapy vol:31 issue:1 pages:30-4
Abstract: Objective: To compare the outcomes of twin-to-twin transfusion syndrome (TTTS) cases treated with fetoscopic laser coagulation of vascular anastomoses before 25 + 6 weeks of gestation and between 26 and 28 weeks of gestation. Material and Methods: 28 consecutive cases of TTTS at Quintero stages II-IV treated with laser therapy between 26 + 0 and 28 + 6 weeks of gestation were compared with 324 cases treated between 15 + 0 and 25 + 6 weeks during a 3-year period in two centers. The following data were recorded and compared: duration of the fetoscopy, rate of complications (preterm labor before 28 weeks and before 32 weeks, chorioamnionitis, twin anemia-polycythemia syndrome and recurrent TTTS), gestational age at delivery and neonatal survival rate. Results: The study groups were similar as regards Quintero staging and the frequency of anterior placental location (50.0 vs. 47.8%, p = 0.85 in late and conventional laser, respectively). There were no significant differences in the duration of surgery (29 vs. 30, p = 0.27, respectively) and in the rates of any of the complications evaluated. Gestational age at delivery (33 vs. 33.3 weeks, p = 0.69) and neonatal survival of at least one fetus (92.3 vs. 88.6%, p = 0.24) were also similar. Conclusion: Fetoscopic laser coagulation for TTTS performed between 26 + 0 and 28 + 6 weeks of gestation was associated with similar outcomes as those observed in cases treated before 26 weeks.
URI: 
ISSN: 1015-3837
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pregnancy, Foetus and Newborn (-)
Section Woman - Miscellaneous (-)
× corresponding author
# (joint) last author

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