Title: Nucleophilic intramolecular cyclization reactions of alkynechalcogenolates
Authors: Abramov, MA ×
Dehaen, Wim
D'hooge, B
Petrov, ML
Smeets, S
Toppet, Suzanne
Voets, M #
Issue Date: Jan-2000
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:56 issue:24 pages:3933-3940
Abstract: 2-(ortho-Hydroxyphenyl)-alkynethiolates and -selenolates, obtained through base catalyzed ring cleavage of 4-(ortho-hydroxy phenyl)-1,2,3-thiadiazoles and -1,2,3-selenadiazoles, smoothly transform into 2-benzofuranthiolates and -selenolates. These reactive intermediates can be alkylated in high yield. This reaction sequence could be applied to the synthesis of electron rich thiacrown ethers. The 2-(ortho-aminophenyl)-alkynethiolate analogously forms 2-methylsulfanylindole. (C) 2000 Elsevier Science Ltd. All rights reserved.
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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