Title: New strategies for low light level detection in single molecule spectroscopy
Authors: Novikov, E ×
Boens, Noël
Hofkens, Johan #
Issue Date: Jan-2001
Publisher: Elsevier science bv
Series Title: Chemical Physics Letters vol:338 issue:2-3 pages:151-158
Abstract: The use of low excitation intensities in single molecule experiments reduces photobleaching and background scatter. Under this condition, detection procedures, which utilize the measured information in an efficient way, should be developed. New statistical procedures based on the measurement of the distribution of the arrival times of the first and single detected photon during the detection interval are proposed. Using simulated data, we show that, for low numbers of detected photons, the new statistical procedures yield more reliable parameter estimates than the commonly used distribution of the number of detected photons per detection interval. (C) 2001 Elsevier Science B.V. All rights reserved.
ISSN: 0009-2614
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Imaging and Photonics
× corresponding author
# (joint) last author

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