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Title: Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis
Authors: van Es, Michael A ×
Schelhaas, Helenius J
van Vught, Paul W J
Ticozzi, Nicola
Andersen, Peter M
Groen, Ewout J N
Schulte, Claudia
Blauw, Hylke M
Koppers, Max
Diekstra, Frank P
Fumoto, Katsumi
Leclerc, Ashley Lyn
Keagle, Pamela
Bloem, Bastiaan R
Scheffer, Hans
van Nuenen, Bart F L
van Blitterswijk, Marka
van Rheenen, Wouter
Wills, Anne-Marie
Lowe, Patrick P
Hu, Guo-Fu
Yu, Wenhao
Kishikawa, Hiroko
Wu, David
Folkerth, Rebecca D
Mariani, Claudio
Goldwurm, Stefano
Pezzoli, Gianni
Van Damme, Philip
Lemmens, Robin
Dahlberg, Caroline
Birve, Anna
Fernández-Santiago, Rubén
Waibel, Stefan
Klein, Christine
Weber, Markus
van der Kooi, Anneke J
de Visser, Marianne
Verbaan, Dagmar
van Hilten, Jacobus J
Heutink, Peter
Hennekam, Eric A M
Cuppen, Edwin
Berg, Daniela
Brown, Robert H
Silani, Vincenzo
Gasser, Thomas
Ludolph, Albert C
Robberecht, Wim
Ophoff, Roel A
Veldink, Jan H
Pasterkamp, R Jeroen
de Bakker, Paul I W
Landers, John E
van de Warrenburg, Bart P
van den Berg, Leonard H #
Issue Date: Dec-2011
Publisher: American Neurological Association
Series Title: Annals of Neurology vol:70 issue:6 pages:964-973
Article number: 10.1002/ana.22611
Abstract: Several studies have suggested an increased frequency of variants in the gene encoding angiogenin (ANG) in patients with amyotrophic lateral sclerosis (ALS). Interestingly, a few ALS patients carrying ANG variants also showed signs of Parkinson disease (PD). Furthermore, relatives of ALS patients have an increased risk to develop PD, and the prevalence of concomitant motor neuron disease in PD is higher than expected based on chance occurrence. We therefore investigated whether ANG variants could predispose to both ALS and PD.
ISSN: 0364-5134
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Experimental Neurology
Laboratory for Neurobiology
× corresponding author
# (joint) last author

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