Title: Microwave-Assisted Decarboxylative Three-Component Coupling of a 2-Oxoacetic Acid, an Amine, and an Alkyne
Authors: Feng, Huangdi ×
Ermolat'ev, Denis S
Song, Gonghua
Van der Eycken, Erik #
Issue Date: Sep-2011
Publisher: American Chemical Society
Series Title: Journal of Organic Chemistry vol:76 issue:18 pages:7608-7613
Abstract: A novel and efficient microwave-assisted decarboxylative three-component coupling of a 2-oxoacetic acid, an amine, and an alkyne (OA(2)-coulpling) has been developed. This new multicomponent coupling constitutes an efficient approach for the synthesis of polysubstituted propargylamines in the presence of a catalytic amount of copper(I) catalyst.
ISSN: 0022-3263
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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