Title: Efficient Pd(0)-mediated microwave-assisted arylation of 2-substituted imidazo[1,2-a]pyrimidines
Authors: Ermolat'ev, D. S ×
Gimenez, V. N
Babaev, E. V
Van der Eycken, Erik #
Issue Date: Jan-2006
Publisher: Amer chemical soc
Series Title: Journal of combinatorial chemistry vol:8 issue:5 pages:659-663
Abstract: A short and practical synthesis of 2,3-substituted imidazo[1,2-a]pyrimidines, based on microwave-assisted Heck-type arylation of 2-substituted imidazo[1,2-a] pyrimidines, was developed. A 45-membered library of 2,3-substituted imidazo[1,2-a] pyrimidines was obtained with good yields and purities using this optimized protocol.
ISSN: 1520-4766
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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