Title: Monitoring of the biological response to murine Hindlimb ischemia with Cu-64-labeled vascular endothelial growth factor-121 positron emission tomography
Authors: Willmann, Jurgen K ×
Chen, Kai
Wang, Hui
Paulmurugan, Ramasamy
Rollins, Mark
Cai, Weibo
Wang, David S
Chen, Ian Y
Gheysens, Olivier
Rodriguez-Porcel, Martin
Chen, Xiaoyuan
Gambhir, Sanjiv S #
Issue Date: Feb-2008
Publisher: Lippincott Williams & Wilkins
Series Title: Circulation vol:117 issue:7 pages:915-922
Abstract: Background-Vascular endothelial growth factor-121 (VEGF(121)), an angiogenic protein secreted in response to hypoxic stress, binds to VEGF receptors (VEGFRs) overexpressed on vessels of ischemic tissue. The purpose of this study was to evaluate Cu-64-VEGF(121) positron emission tomography for noninvasive spatial, temporal, and quantitative monitoring of VEGFR2 expression in a murine model of hindlimb ischemia with and without treadmill exercise training.
ISSN: 0009-7322
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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