Title: EGFR-targeted therapy
Authors: Vecchione, Loredana ×
Jacobs, Bart
Normanno, Nicola
Ciardiello, Fortunato
Tejpar, Sabine #
Issue Date: Nov-2011
Publisher: Academic Press
Series Title: Experimental Cell Research vol:317 issue:19 pages:2765-2771
Abstract: Anti-Epidermal Growth Factor Receptor (EGFR) therapies have been recently developed for the treatment of multiple cancer types. At the time when they were introduced in clinical practice, there was little knowledge of the molecular bases of tumor sensitivity and resistance to these novel targeted compounds. By using the framework of anti-EGFR inhibitors as treatment for colorectal cancer patients, we will review the knowledge we have reached until now in improving the development of a personalized cancer therapy and we will try to indicate the future challenges this field will face in the future. (C) 2011 Elsevier Inc. All rights reserved.
ISSN: 0014-4827
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Digestive Oncology (+)
Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science