Lack of efficacy of long-term, low-dose azithromycin in chronic rhinosinusitis: a randomized controlled trial
Videler, W J × Badia, L Harvey, R J Gane, S Georgalas, C van der Meulen, F W Menger, D J Lehtonen, M T Toppila-Salmi, S K Vento, S I Hytönen, M Hellings, Peter Kalogjera, L Lund, V J Scadding, G Mullol, J Fokkens, W J #
John Wiley & Sons, Inc.
Allergy vol:66 issue:11 pages:1457-68
In persistent chronic rhinosinusitis (CRS), conventional treatment is often insufficient. Long-term, low-dose administration of macrolides has been suggested as a treatment option. The MACS (Macrolides in chronic rhinosinusitis) study is a randomized placebo-controlled trial evaluating the efficacy of azithromycin (AZM) in CRS.