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Title: Reaction of heterocyclic thioamides with dimethyl acetylenedicarboxylate. Synthesis of novel 2-azolyl-5-methoxycarbonylmethylene thiazolin-4-ones
Authors: Berseneva, VS ×
Morzherin, YY
Dehaen, Wim
Luyten, Ingrid
Bakulev, VA #
Issue Date: Jan-2001
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron vol:57 issue:11 pages:2179-2184
Abstract: A systematic study of the reactions of dimethyl acetylenedicarboxylate (DMAD) with heterocyclic thioamides has been carried out and a number of new 2-isoxazolyl-(8), imidazolyl-(13a,b and 17a), 1,2,3-triazolyl-(13d,e) and 1,2,3-thiadiazolyl (17b) thiazolines have been prepared. The higher reactivity of the thioamide group in comparison with the amino group in these reactions has been established. (C) 2001 Elsevier Science Ltd. All rights reserved.
URI: 
ISSN: 0040-4020
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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