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Chemistry and physics of lipids

Publication date: 2006-01-01
Volume: 139 Pages: 54 - 67
Publisher: Elsevier ireland ltd

Author:

Pfeiffer, Helge
Klose, G ; Heremans, Karel ; Glorieux, Christ

Keywords:

phospholipid, surfactant, differential scanning calorimetry, ultrasonic velocimetry, eutectic, peritectic, compound, phospholipid model membranes, ideal liquid-mixtures, lipid-bilayers, density-fluctuations, nonionic surfactant, water-systems, hydration, solubilization, velocity, transitions, Science & Technology, Life Sciences & Biomedicine, Biochemistry & Molecular Biology, Biophysics, PHOSPHOLIPID MODEL MEMBRANES, IDEAL LIQUID-MIXTURES, LIPID-BILAYERS, DENSITY-FLUCTUATIONS, NONIONIC SURFACTANT, WATER-SYSTEMS, HYDRATION, SOLUBILIZATION, VELOCITY, TRANSITIONS, 1,2-Dipalmitoylphosphatidylcholine, Calorimetry, Differential Scanning, Chemical Phenomena, Chemistry, Physical, Dimyristoylphosphatidylcholine, Ethers, Membranes, Artificial, Polyethylene Glycols, Rheology, Solutions, Thermodynamics, Water, 02 Physical Sciences, 03 Chemical Sciences, 11 Medical and Health Sciences, 3101 Biochemistry and cell biology, 3205 Medical biochemistry and metabolomics

Abstract:

The present paper reports oil the phase behaviour of the pseudobinary aqueous mixtures of 1,2-dipalniitoyl-sn-glycero-3-phosphocholine (DPPC)/pentaethylene glycol monododecyl ether (C12E5) and 1,2-dimyristoyi-sn-glycero-3-phosphocholine monohydrate (DMPC)/C12E5. Both systems exhibit a variety of rnesophases, such as lamellar gel, liquid crystalline and micellar phases. The phase diagrams show peritectic and eutectic behaviours. The existence of a compound complex is established.