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Title: Relief of sleep apnea after treatment of acromegaly - report of three cases and review of the literature
Authors: Buyse, Bertien ×
Michiels, Els
Bouillon, Roger
Bobbaers, Herman
Demedts, Maurits #
Issue Date: 1997
Publisher: Published jointly by the European Society for Clinical Respiratory Physiology and Munksgaard
Series Title: European Respiratory Journal. Supplement vol:10 pages:1401-1404
Abstract: Sleep apnoea syndrome (SAS) is common in acromegalic patients. Occasionally, the relief of apnoeas after treatment of the acromegaly has been documented. We report the cases of three patients with acromegaly and severe obstructive sleep apnoea, who demonstrated a manifest improvement (respiratory disturbance index (RDI) <20) after treatment with octreotide, indicating that this drug may be effective in this disturbance. In one case, SAS disappeared although the growth hormone level was not fully normalized. This raises the intriguing hypothesis that octreotide has an effect on respiratory control or on the upper airway, that is not directly related to its action on production of growth hormone.
URI: 
ISSN: 0904-1850
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pneumology
Laboratory for Clinical Infectious and Inflammatory Disorders
Clinical and Experimental Endocrinology
× corresponding author
# (joint) last author

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