Gene expression profiles associated with the presence of a fibrotic focus and the growth pattern in lymph node-negative breast cancer
Van den Eynden, Gert G × Smid, Marcel Van Laere, Steven Colpaert, Cecile G Van der Auwera, Ilse Bich, Trinh Xuan van Dam, Peter den Bakker, Michael A Dirix, Luc Y Van Marck, Eric A Vermeulen, Peter B Foekens, John A #
Association for Cancer Research
Clinical Cancer Research vol:14 issue:10 pages:2944-52
A fibrotic focus, the scar-like area found in the center of an invasive breast tumor, is a prognostic parameter associated with an expansive growth pattern, hypoxia, and (lymph)angiogenesis. Little is known about the molecular pathways involved.