This paper presents the result of an investigation of underground conduits, which connect the swallow holes and the resurgence of a blind river in the tropical, highly karstified limestone Nam La catchment in the NW of Vietnam. The Nam La River disappears underground in several swallow holes near the outlet of the catchment. In the rainy season this results in flooding upstream of the sinkholes. A hypothesis is that the Nam La River resurges at a large cavern spring 4.5 km east of the catchment outlet. A multi-thematic study of the possible connections between the swallow holes and the resurgence was carried out to investigate the geological structure, tectonics, cave structure analysis and discharge time series. The existence of the underground conduits was also tested and proven by tracer experiments. On the basis of a lineament analysis the location of the underground conduits were predicted. A remote sensing derived lineament-length density map was used to track routes from the swallow holes to the resurgence, having the shortest length but highest lineament density. This resulted in a plan-view prediction of underground conduits that matches with the cave and fault development. The functioning of the conduits was further explained by analysing flooding records of a nearby doline, which turns out to act as a temporary storage reservoir mitigating flooding of the catchment outlet area.