The Strategic Reperfusion Early After Myocardial Infarction (STREAM) study
Armstrong, Paul W × Gershlick, Anthony Goldstein, Patrick Wilcox, Robert Danays, Thierry Bluhmki, Erich Van de Werf, Frans #
American Heart Journal vol:160 issue:1 pages:30-U49
Background Primary percutaneous coronary intervention (PCI) has emerged as the preferred therapy for acute ST-elevation myocardial infarction (STEMI) provided it is performed in a timely fashion at an expert 24/7 facility. Fibrinolysis is a well-accepted alternative, especially in patients presenting early after symptom onset. The STREAM study will provide novel information on whether prompt fibrinolysis at first medical contact, followed by timely catheterization or rescue coronary intervention in STEMI patients presenting within 3 hours of symptom onset, represents an appropriate alternative strategy to primary PCI.