Title: Excellent survival after liver transplantation for isolated polycystic liver disease: an European Liver Transplant Registry study
Authors: van Keimpema, Loes ×
Nevens, Frederik
Adam, René
Porte, Robert J
Fikatas, Panagiotis
Becker, Thomas
Kirkegaard, Preben
Metselaar, Herold J
Drenth, Joost P H
for the European Liver and Intestine Transplant Association (ELITA) #
Issue Date: Dec-2011
Publisher: Springer International
Series Title: Transplant International vol:24 issue:12 pages:1239-1245
Article number: 10.1111/j.1432-2277.2011.01360.x
Abstract: Patients with end-stage isolated polycystic liver disease (PCLD) suffer from incapacitating symptoms because of very large liver volumes. Liver transplantation (LT) is the only curative option. This study assesses the feasibility of LT in PCLD. We used the European Liver Transplant Registry (ELTR) database to extract demographics and outcomes of 58 PCLD patients. We used Kaplan-Meier survival analysis for survival rates. Severe abdominal pain (75%) was the most prominent symptom, while portal hypertension (35%) was the most common complication in PCLD. The explantation of the polycystic liver was extremely difficult in 38% of patients, because of presence of adhesions from prior therapy (17%). Karnofsky score following LT was 90%. The 1- and 5-year graft survival rate was 94.3% and 87.5%, while patient survival rate was 94.8% and 92.3%, respectively. Survival rates after LT for PCLD are good.
ISSN: 0934-0874
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hepatology
× corresponding author
# (joint) last author

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