Title: Kidney cancer: surgery including nephron-sparing surgery
Authors: Van Poppel, Hendrik #
Issue Date: May-2011
Publisher: Elsevier science inc
Host Document: Critical reviews in oncology hematology vol:78 pages:S6-S6
Conference: European School of Oncology Educational Cancer Lugano Convention Workshop on Whats New and Whats True in Genito-Urinary Oncology Lugano, SWITZERLAND, MAY 12-14, 2011
Article number: 8
Abstract: Kidney cancer is the most lethal of urological cancers and
there is an increased incidence over the years. Although
renal cell carcinoma is more often diagnosed in early stages,
there is no decline in kidney cancer mortality. In 1963,
radical nephrectomy was introduced as standard treatment
for localized renal cell carcinoma by Robson but many
other potential therapeutic options have arisen as a result of
the increased number of small tumors and the advances in
surgical technology. In an attempt to minimize operative
morbidity, minimally invasive options like laparoscopic
radical and partial nephrectomy, cryoablation, radiofrequency
ablation and high intensity focused ultrasound are being
Controversy remains indications for simultaneous adrenalectomy
and lymphadenectomy in patients undergoing radical
Open partial nephrectomy is in expert centers more and
more replaced by laparoscopic, eventually robot assisted
procedures that minimize the inconveniences of open surgery
through mostly a lumbar approach. Partial nephrectomy has
become standard treatment for small solid renal masses.
Patients with venous extension at the level of the renal vein
or the inferior vena cava often present without evidence of
lymph nodes or distant metastases and a complete resection
will bring cure in a number of them. Here open surgical
expertise will be necessary.
Percutaneous radiofrequency ablation and laparoscopic or
percutaneous cryoablation are now more and more often
proposed and show promising results mostly in patients that
are not fit for surgery. The possibility of performing these
ablations on an outpatient basis with much less complications
and costs will induce further exploration of these minimal
invasive techniques.
ISSN: 1040-8428
Publication status: published
KU Leuven publication type: IMa
Appears in Collections:Urology Section (-)
# (joint) last author

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