Title: Synthesis of novel functionalised symmetric bi-2(1H)-pyrazinones
Authors: De Borggraeve, Wim ×
Appukkuttan, P
Azzam, R
Dehaen, Wim
Compernolle, Frans
Van der Eycken, Erik
Hoornaert, Georges #
Issue Date: Jan-2005
Publisher: Georg thieme verlag kg
Series Title: Synlett issue:5 pages:777-780
Abstract: A simple and convenient synthesis for functionalised bi-2(1H)-pyrazinones 9, 11a-h starting from 3,5-dichloro-2(1H)pyrazinones 7, 10a-h is described. The pyrazinone is homo-coupled by means of a Suzuki-type reaction of an in situ generated boronate. The reactions were carried out under conventional heating as well as under microwave irradiation and dramatic improvements in the rates and yields have been observed under the latter conditions.
ISSN: 0936-5214
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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