Title: [3+2]- versus [4+2]-cycloaddition reactions of 3-methylsulfanyl-2-arylazo-3-(pyrrolidin-1-yl)acrylonitriles with N-substituted maleimides involving pyrrolidine-derived azomethine ylides
Authors: Deryabina, TG ×
Belskaia, NP
Kodess, MI
Dehaen, Wim
Toppet, Suzanne
Bakulev, VA #
Issue Date: Jan-2006
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron letters vol:47 issue:11 pages:1853-1855
Abstract: 3-Methylsulfanyl-2-arylazo-3-(pyrrolidin-1-yl)acrylonitriles do not enter into [4+2]-cycloaddition reactions with male-imides to form the expected pyrrolo-pyridazines. Instead the formation of novel pyrrolo-pyridazines of type 4 takes place via a formal [3+2]-cycloaddition of initially formed pyrrolidine-derived azomethine ylides 7. The mechanism leading to the final product is discussed. (c) 2006 Elsevier Ltd. All rights reserved.
ISSN: 0040-4039
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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