Title: Temporal Diffeomorphic Free-Form Deformation for Strain Quantification in 3D-US Images
Authors: De Craene, Mathieu
Piella, Gemma
Duchateau, Nicolas
Silva, Etel
Doltra, Adelina
Gao, Hang
D'hooge, Jan
Camara, Oscar
Brugada, Josep
Sitges, Marta
Frangi, Alejandro F #
Issue Date: 2010
Publisher: Springer-verlag berlin
Host Document: Medical image computing and computer-assisted intervention - miccai 2010, pt ii, vol:6362 pages:1-8
Series Title: Lecture Notes in Computer Science
Conference: 13th International Conference on Medical Image Computing and Computer-Assisted Intervention Beijing, PEOPLES R CHINA, SEP 20-24, 2010
Abstract: This paper presents a new diffeomorphic temporal registration algorithm and its application to motion and strain quantification from a temporal sequence of 31) images. The displacement field is computed by forward eulerian integration of a non-stationary velocity field. The originality of our approach resides in enforcing time consistency by representing the velocity field as a sum of continuous spatiotemporal B-Spline kernels. The accuracy of the developed diffeomorphic technique was first compared to a simple pairwise strategy on synthetic US images with known ground truth motion and with several noise levels, being the proposed algorithm more robust to noise than the pairwise case. Our algorithm was then applied to a database of cardiac 3D+t Ultrasound (US) images of the left ventricle acquired from eight healthy volunteers and three Cardiac Resynchronization Therapy (CRT) patients. On healthy cases, the measured regional strain curves provided uniform strain patterns over all myocardial segments in accordance with clinical literature. On CRT patients, the obtained normalization of the strain pattern after CRT agreed with clinical outcome for the three cases.
ISBN: 978-3-642-15744-8
ISSN: 0302-9743
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Cardiovascular Imaging and Dynamics
# (joint) last author

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