Title: Breast Cancer Susceptibility Polymorphisms and Endometrial Cancer Risk: a Collaborative Endometrial Cancer Study
Authors: Healey, Catherine S ×
Ahmed, Shahana
AOCS Management Group
O'Mara, Tracy
Ferguson, Kaltin
Lambrechts, Diether
Garcia-Dios, Diego A
Vergote, Ignace
Amant, Frederic
Howarth, Kimberley
Gorman, Maggie
Hodgson, Shirley
Tomlinson, Ian
Yang, Pecs-Hannah P
Lissowska, Jola
Brinton, Louise A
Chanock, Stephen
Garcia-Closas, Montserrat
Hall, Sasbac-Per
Liu, Jianjun
Shah, Search-Mitul
Pharoah, Paul Dp
Thompson, Deborah
Timothy, R Rebbeck
Strom, Brian L
Dunning, Alison M
Easton, Douglas F
Spurdle, Amanda B #
Issue Date: Dec-2011
Publisher: IRL Press
Series Title: Carcinogenesis vol:32 issue:12 pages:1862-1866
Abstract: Recent large-scale association studies, both of genome wide and candidate gene design, have revealed several single nucleotide polymorphisms (SNPs) which are significantly associated with risk of developing breast cancer. As both breast and endometrial cancers are considered to be hormonally driven and share multiple risk factors, we investigated whether breast cancer risk alleles are also associated with endometrial cancer risk. We genotyped nine breast cancer risk SNPs in up to 4,188 endometrial cases and 11,928 controls, from between three and seven Caucasian populations. None of the tested SNPs showed significant evidence of association with risk of endometrial cancer.
ISSN: 0143-3334
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Vesalius Research Centre (-)
Gynaecological Oncology
Laboratory of Translational Genetics (Vesalius Research Center) (+)
× corresponding author
# (joint) last author

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