Title: An improved synthesis of n-6-(6-aminohexyl)fad
Authors: Saleh, A ×
Compernolle, Frans
Janssen, Gerardus #
Issue Date: Jan-1995
Publisher: Marcel dekker inc
Series Title: Nucleosides & nucleotides vol:14 issue:3-5 pages:689-692
Abstract: We report an improved synthesis of N-6-(6-aminohexyl)FAD (1) using an efficient one-pot conversion of inosine to the N-trifluoroacetyl protected N-6-(6-aminohexyl)adenosine 3. The 5'-O-phosphorylated AMP derivative 4, activated as the imidazolide, was coupled with commercial sodium riboflavin phosphate by using 18-crown-6 in DMF.
ISSN: 0732-8311
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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