Title: Occupational noise, smoking, and a high body mass index are risk factors for age-related hearing impairment and moderate alcohol consumption is protective: a European population-based multicenter study
Authors: Fransen, Erik ×
Topsakal, Vedat
Hendrickx, Jan-Jaap
Van Laer, Lut
Huyghe, Jeroen R
Van Eyken, Els
Lemkens, Nele
Hannula, Samuli
Mäki-Torkko, Elina
Jensen, Mona
Demeester, Kelly
Tropitzsch, Anke
Bonaconsa, Amanda
Mazzoli, Manuela
Espeso, Angeles
Verbruggen, Katia
Huyghe, Joke
Huygen, Patrick L M
Kunst, Sylvia
Manninen, Minna
Diaz-Lacava, Amalia
Steffens, Michael
Wienker, Thomas F
Pyykkö, Ilmari
Cremers, Cor W R J
Kremer, Hannie
Dhooge, Ingeborg
Stephens, Dafydd
Orzan, Eva
Pfister, Markus
Bille, Michael
Parving, Agnete
Sorri, Martti
Van de Heyning, Paul
Van Camp, Guy #
Issue Date: Sep-2008
Publisher: Springer-Verlag New York Inc.
Series Title: Journal of the Association for Research in Otolaryngology vol:9 issue:3 pages:264-76; discussion 261-3
Abstract: A multicenter study was set up to elucidate the environmental and medical risk factors contributing to age-related hearing impairment (ARHI). Nine subsamples, collected by nine audiological centers across Europe, added up to a total of 4,083 subjects between 53 and 67 years. Audiometric data (pure-tone average [PTA]) were collected and the participants filled out a questionnaire on environmental risk factors and medical history. People with a history of disease that could affect hearing were excluded. PTAs were adjusted for age and sex and tested for association with exposure to risk factors. Noise exposure was associated with a significant loss of hearing at high sound frequencies (>1 kHz). Smoking significantly increased high-frequency hearing loss, and the effect was dose-dependent. The effect of smoking remained significant when accounting for cardiovascular disease events. Taller people had better hearing on average with a more pronounced effect at low sound frequencies (<2 kHz). A high body mass index (BMI) correlated with hearing loss across the frequency range tested. Moderate alcohol consumption was inversely correlated with hearing loss. Significant associations were found in the high as well as in the low frequencies. The results suggest that a healthy lifestyle can protect against age-related hearing impairment.
ISSN: 1525-3961
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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