Title: Cervical thymus in the mouse
Authors: Dooley, James ×
Erickson, M
Gillard, GO
Farr, AG #
Issue Date: Jun-2006
Publisher: American Association of Immunologists
Series Title: Journal of Immunology vol:176 issue:11 pages:6484-6490
Abstract: Although thymic ectopy has long been recognized in humans, the functional activity or potential immunological significance of this thymic tissue is unknown. In this study, we describe murine thymic ectopy, cervical thymic tissue that possesses the same general organization as the thoracic thymus, that is able to support T cell differentiation, and that can export T cells to the periphery. Unexpectedly, the pattern of autoantigen expression by ectopic thymic tissue differs from that of the thoracic thymus, raising the possibility that these two thymic environments may project different versions of self.
ISSN: 0022-1767
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Genetics of Autoimmunity
× corresponding author
# (joint) last author

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