Title: Use of the N-tosyl-activated aziridine 1,2-dideoxy-1,2-iminomannitol as a synthon for 1-deoxymannojirimycin analogues
Authors: Joly, GJ ×
Peeters, K
Mao, H
Brossette, Thierry
Hoornaert, GJ
Compernolle, Frans #
Issue Date: Jan-2000
Publisher: Pergamon-elsevier science ltd
Series Title: Tetrahedron letters vol:41 issue:13 pages:2223-2226
Abstract: 1-Amino-1-deoxy-D-glucitol was converted into the selectively protected title compound 4, an N-tosyl-activated aziridine that readily underwent ring opening with various nucleophiles. Further deprotection of the 5,6-diol moiety followed by ring closure under Mitsunobu conditions afforded the corresponding 6-substituted analogues of 1-deoxymannojirimycin. (C) 2000 Elsevier Science Ltd. All rights reserved.
ISSN: 0040-4039
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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