Tetrasubstituted 2-Imidazolones via Ag(I)-Catalyzed Cycloisomerization of Propargylic Ureas
Peshkov, Vsevolod A × Pereshivko, Olga P Sharma, Sweta Meganathan, Thirumal Parmar, Virinder S Ermolat'ev, Denis S Van der Eycken, Erik #
American Chemical Society
Journal of Organic Chemistry vol:76 issue:14 pages:5867-5872
A one-pot protocol based on a Ag(I)-catalyzed cycloisomerization of propargylic ureas, derived from secondary propargylamines and isocyanates, was developed for the generation of the 2-imidazolone core.