Title: Functional involvement of PHOSPHO1 in matrix vesicle-mediated skeletal mineralization
Authors: Roberts, Scott ×
Narisawa, Sonoko
Harmey, Dympna
Millán, José Luis
Farquharson, Colin #
Issue Date: Apr-2007
Publisher: Blackwell Science, Inc.
Series Title: Journal of Bone and Mineral Research vol:22 issue:4 pages:617-27
Abstract: PHOSPHO1 is a phosphatase highly expressed in bone. We studied its functional involvement in mineralization through the use of novel small molecule inhibitors. PHOSPHO1 expression was present within matrix vesicles, and inhibition of enzyme action caused a decrease in the ability of matrix vesicles to calcify.
ISSN: 0884-0431
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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