Biochemical Society Transactions vol:39 pages:1527-1532
Despite the availability of various classes of antimycotics, the treatment of patients with systemic fungal
infections is challenging. Therefore the development of new antifungals is urgently required. Promising
new antifungal candidates are antimicrobial peptides. In the present review, we provide an overview of
antifungal peptides isolated from plants, insects, amphibians and mammals that induce apoptosis. Their
antifungal spectrum, mode of action and toxicity are discussed in more detail.